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Themed collection Coronavirus articles - free to access collection

156 items - Showing page 1 of 3
Editorial

Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research

英国会是七国集团(G7)中经济增长最慢的国家吗?
金发女郎乐队《花粉传播者》

Graphical abstract: Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research
Editorial

Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?

对于其他队伍而言,在球场上拥有良好判断力的德国也是一直非常出色的队伍。意大利也是世界杯上无法忽视的队伍,而拥有罗纳尔多的葡萄牙队将会是一直极具危险性的队伍。拥有众多的大将的比利时队也将成为人们口中津津乐道的黑马队伍。
While 221 people fell off the billionaires list this year, 198 people joined the ranks. Twenty-nine from the 2015 list died, while another 29 rejoined the list after having fallen off.

Graphical abstract: Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?
From the themed collection: 离婚说好房产给孩子 不能变卦
Open Access Accepted Manuscript - Highlight

Nano and biosensors for detection of SARS-CoV-2: challenges and opportunities

From the themed collection: 北京:统筹实施土地资源整理
Open Access Perspective

Soft matter science and the COVID-19 pandemic

NASA和另一个保持长期气温记录的美国机构、国家海洋和大气管理局在上周五发布了各自的数据汇编,证实了2014年是创纪录的一年。一家日本机构曾在一月初发布初步信息显示,2014年是最热的一年。

Graphical abstract: Soft matter science and the COVID-19 pandemic
From the themed collection: 海尔联姻 撬动智能家居千亿市场
Open Access Perspective

Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective

As consumers in developing countries continue to shift to meat-based diets, grains and oilseeds used as livestock feed are expected to see support.

Graphical abstract: Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective
From the themed collection: 陶瓷企业与供应商“智斗”内幕
Perspective

Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic

British statisticians’ unwillingness to correct known errors in the clothing price component of the RPI redistributes many billions every year from students, recent graduates, taxpayers and rail commuters to index-linked UK government bondholders, wealthy pensioners with RPI-linked pensions and rail companies.
n. 马厩,
报告还显示,2012年以来,企业养老保险累计结余虽不断扩大,但可支付月数由2012年的19.7个月下降至2015年的17.7个月。
It’s the time of the year for list making! This Youku video clip named the nine hottest lines on China’s web this year. The Yangtze Evening Post, an influential newspaper, is the original list compiler.

Graphical abstract: Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic
Perspective

Trends and targets in antiviral phototherapy

Extreme heat blanketed Alaska and much of the western United States last year. Records were set across large areas of every inhabited continent. And the ocean surface was unusually warm virtually everywhere except near Antarctica, the scientists said, providing the energy that fueled damaging Pacific storms.
我们要咬定青山不放松,持之以恒为群众办实事、解难事,促进社会公平正义,把发展硬道理更多体现在增进人民福祉上。
Major areas of work for 2017
toxic

Graphical abstract: Trends and targets in antiviral phototherapy
Minireview

A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays

He did several makeup tests to get the look that would so dramatically change Mr. Carell. “We were literally creating a new human being,” Mr. Corso said.

Graphical abstract: A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays
Minireview

Novel biosensing methodologies for ultrasensitive detection of viruses

“This young Vermonter clearly has an interest in service and anyone putting ideas forward with the goal of making Vermont a better place is appreciated here,” Scott's spokeswoman, Rebecca Kelley, tells PEOPLE.

Graphical abstract: Novel biosensing methodologies for ultrasensitive detection of viruses
Application

Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug

Are you heading to Rio for the Olympics? Will you leverage the Google Maps app on Android or iOS? I think you already have the answer.
朱迪·福斯特(Jodie Foster)过去也将洗手间作为最佳选择 –“它们和水龙头看起来交相辉映”–但她已经为因影片《沉默的羔羊》(The Accused and Silence of the Lambs)获得的两尊小金人找到了一个更好的归属:奖杯盒。

Graphical abstract: Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug
Open Access Review Article

ACE2 as a potential therapeutic target for pandemic COVID-19

She argues, however, that the problems with lower liquidity of ETFs in Asia are a symptom of a fund distribution system that fails to incentivise ETF sales by intermediaries. “I don't think there is a quick fix, but you would see a pick-up if Asia moves to a fee-based model,” she says.
Agricultural raw materials, especially the so called soft commodities such as sugar, coffee and cotton, have been among the top performers this year.

Graphical abstract: ACE2 as a potential therapeutic target for pandemic COVID-19
Open Access Review Article

Diagnostic technologies for COVID-19: a review

Employees of state-owned firms also expressed more satisfaction with their bonuses than those at private companies – and little wonder, as the average payout at the former was Rmb17,318, or about Rmb6,000 more than what their private-sector counterparts could expect.
推动社会治理创新。

Graphical abstract: Diagnostic technologies for COVID-19: a review
Open Access Review Article

Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review

Wallace wrote the book after saying "yes" to everything for a year, a commitment which both advanced his career and landed him in a cult meeting. What the movie didn't show, however, is the sheer number of Internet scams Wallace signed up for. Apparently, saying "yes" all the time has its downfalls in real life.
Enrollment: NA
Ms Lewis urged people to contact family, neighbours or an animal shelter if they were no longer able to care for their pets.
ceremony

Graphical abstract: Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review
Open Access Review Article

An overview of key potential therapeutic strategies for combat in the COVID-19 battle

去年12月份达成的预算协议很难称得上是华盛顿激辩多年所希望看到的、能够提振信心的协议,但至少它为华盛顿不断上演的政治博弈按下了“暂停”键。在过去三年中,华盛顿每年都会上演的这种博弈对经济的复苏构成了威胁。

Graphical abstract: An overview of key potential therapeutic strategies for combat in the COVID-19 battle
From the themed collection: 进一步完善三地协同政策评价体系
Open Access Review Article

Potential repurposed SARS-CoV-2 (COVID-19) infection drugs

Two against-the-clock tours of Los Angeles. Two celebrations of the sometimes prickly solidarity among women. Four tremendous performances, from Kitana Kiki Rodriguez, Mya Taylor, Julia Garner and the great Lily Tomlin. “Grandma” is the work of a studio veteran. “Tangerine” was shot on iPhones. Anyone prone to lamenting the death of movies needs to shut up and watch these.
但现实远比他想象的艰难。雷文斯克罗夫特表示:“我曾以为这就是一个机会,要花掉两年,但现实是严峻的,因为这活不好干。”此外,他的导师在雷曼兄弟(Lehman Brothers)工作,这家银行于2008年破产。他大笑着说:“这段指导关系持续的时间没有我希望的那么长。”

Graphical abstract: Potential repurposed SARS-CoV-2 (COVID-19) infection drugs
Open Access Review Article

Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale

Below are a number of statements that people often use to describe themselves.

Graphical abstract: Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale
Review Article

In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections

The company realised that "it was all a mistake and that he did it without thinking," a Google spokeswoman said last Wednesday.

Graphical abstract: In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections
Review Article

Antiviral drug discovery: broad-spectrum drugs from nature

[k?ut?]
3.体操类比赛项目
3.解决问题的好手
在气候学的史册里,2014年超过了2010年,成为最热的年份。有记录以来的10个最暖年份都是在1997年以后,反映了地球不断变暖的趋势,科学家说,这种变暖是人类活动的结果,并对人类文明和大自然构成了深远的长期危险。

Graphical abstract: Antiviral drug discovery: broad-spectrum drugs from nature
From the themed collection: 谨防土地财政 掣肘楼市去库存
Review Article

Influenza neuraminidase: A druggable target for natural products

"How many patients do Chinese doctors see a day? It can be more than 50," he told China Daily. "How can we have the time and energy to do research or publish papers?"
20. 对电影爱好者的最佳建议。8月学者韦勒·温斯顿·迪克森(Wheeler Winston Dixon)发出了警告:“如果你上亚马逊,看到什么精彩的黑白电影卖三美元,或者其他什么外国电影和鲜为人知的电影,赶快买下来,因为它就要绝版了,他们不会再出版它们了。”成千上万这种VHS格式的电影不会被做成DVD格式或蓝光格式,迪克森警告说。而下载的美丽新世界(又名电子销售)明年将是好年头。
2. paparazzo /[复] paparazzi / n . 专门追逐名人偷拍照片的摄影者(或记者),狗仔队。
1q_LRV!0kJXXtQDOIg7_
达洛伊西奥也尽力维持着生活原本的样子。他的女友还是之前的那个女友。而且尽管他不再去学校了──坐在教室里就没空监管Summly的研发──他还是照常去找老师拿作业。他十分庆幸他的朋友不了解他企业家的那一面。而当我采访他的时候,他正准备和一群高中死党去希腊玩上一周。

Graphical abstract: Influenza neuraminidase: A druggable target for natural products
Critical Review

Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle

The quality of its students makes LBS particularly valued. “Studying among so many talented people has instilled in me the belief that I can actually achieve something on my own,” comments one MBA graduate from the class of 2011.
Hugo Boss, Chevrolet and Kleenex dropped off the list, the report said.

Graphical abstract: Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle
Critical Review

The role of biosensors in the detection of emerging infectious diseases

5.ah, you look great in that dress. – Because it’s better than being slapped。

Graphical abstract: The role of biosensors in the detection of emerging infectious diseases
Communication

Quantitative determination of mechanical stability in the novel coronavirus spike protein

In fact, one ancient saying was, "ifyou have Kucha, only one percent of the states in the Western Frontiers remain unsubmissive."

Graphical abstract: Quantitative determination of mechanical stability in the novel coronavirus spike protein
Communication

Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations

《皮囊之下》就是如此的直观如此的自由不羁,抛开欢快,离奇的剧情和电影本身的情色——一切都处于黑暗中,摧毁性的性爱中。它是一种力量,在你的皮囊之下。
据Mic上周报道,脸书表情包分享群组已经成为一个新兴的大学传统,全国各地的学生们用截图和配字互开玩笑,与对手学校互怼。
时间:2010-01-29 编辑:vicki
源于:relax(v 放松;休息)

Graphical abstract: Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations
From the themed collection: 恒康家居拟A股上市募资5.67亿
Communication

MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling

demonstration
但是,海外机构投资者表示,随着中国经济增长放慢,香港房地产市场已经过热,正在进入调整阶段。
Scientists may be working hard at making organs that match the body's capabilities, but why stop there?
'In the next 12 to 24 months, unless any of these bottlenecks are solved, we could see WTI going down to $50 a barrel, to incentivize producers to slow down,' she said

Graphical abstract: MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling
Communication

Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses

Bernard Baumohl 作为Economic Outlook Group的首席经济学家,表示他甚至更乐观的认为接下来的两年将会成为至少近十年以来形势最好的两年,他还称“有很多证据充分的表明了经济正在恢复的势头”。
vt. 为 .

Graphical abstract: Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses
Communication

Inhibition of SARS coronavirus helicase by bismuth complexes

They appeared in high spirits despite losing three-nil to Belgium on Saturday .
万分沮丧之下,他发明了可以允许自拍的东西:他称之为"伸缩杆"。因为智能手机还没发明出来,所以,连接在自拍杆末端的是一个微型相机。在杆的前端有一面小镜子,方便使用者调整他们在相机里的姿态。他在1983年为"伸缩杆"申请了专利。虽然自拍杆进行了大量生产出售,却属商业败笔——相片的质量比较差。另外,以前的研究表明,那时的女士会因自己有自拍的想法而感到尴尬。在2000年,自拍杆被韦恩·弗洛姆(Wayne Fromm)重新发明,那时,上田宏的"伸缩杆"专利期尚有三年。弗洛姆称他的自拍杆为"快捷豆荚"。他认为他才是当今自拍杆的发明者,甚至起诉其他自拍杆生产者。当被问到上田宏的自拍杆时,弗洛姆评论说它们是"先前的艺术"。
Russia and Nato have both called for a de-escalation of the Turkey-Netherlands row.
Chester Bennington
n. 精美的东西

Graphical abstract: Inhibition of SARS coronavirus helicase by bismuth complexes
From the themed collection: 长租品牌公寓成为租客新宠
Open Access Edge Article

Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning

当时,身为首席执行官的库克也承受着压力,因为苹果除了从iPhone攫取利润之外,缺乏清晰的产品开发方向。维权投资者嗅到了血腥,开始围攻这家公司,打头的是大卫?艾因霍恩(David Einhorn),接着是卡尔?伊坎(Carl Icahn),他们游说改变苹果的经营和财务管理方式。伊坎施压要求苹果筹集巨额债务,向股东返还1500亿美元,并敦促苹果发布包括电视机在内的更多产品。
The reality turned out to be tougher than he imagined. “I saw it as a two-year opportunity,” says Mr Ravenscroft. “The grinding reality is that it’s a slog.” Moreover, his mentor worked at Lehman Brothers, the bank that collapsed in 2008. “It wasn’t quite as long a mentoring relationship as I’d hoped,” he laughs.
n. 购买,购买的物品

Graphical abstract: Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning
Open Access Edge Article

A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers

《美国谍梦》(The Americans):FX频道的这部电视剧以里根时代为背景,它和剧中两位伪装成美国郊区夫妻的克格勃间谍一样具有欺骗性:第二季表面上看是冷战惊悚剧,实际上是关于爱情、家庭、友谊和猜忌的情节剧。
The fact is, Hon Lik is not the first person to invent the e-cigarette. Way back in 1963, Herbert Gilbert made the world's first device that could be used to inhale tobacco-flavored air. In Gilbert's original version, there was no form of combustion and it was free of nicotine. He later designed a prototype that used a battery to create heat. He also used different flavors of water to create steam. He presented his prototypes to different chemical, pharmaceutical, and tobacco companies, but they simply turned down his prototypes.

Graphical abstract: A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers
Open Access Edge Article

Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods

The molecular mechanism of the proteolysis reaction catalyzed by SARS-CoV-2 Mpro, one of the enzymes essential for the replication process of the virus responsible for the COVID-19 pandemic, is described using computational QM/MM methods.

Graphical abstract: Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods
From the themed collection: 10个数据见证中国涂料百年沧桑
Open Access Edge Article

Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors

By combining evolutionary and physico-chemical principles, previously unknown druggable Zn-sites in multiple conserved SARS-CoV-2 domains have been identified.

Graphical abstract: Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors
Open Access Edge Article

Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir

他补充说,原本的故事情节里有个无法回避的问题,因为格洛本来的设定是个深陷对邦德的欲望而无法自拔的女同性恋。
《发生什么了,西蒙妮小姐?》(What Happened, Miss Simone?),导演:利兹·加布斯(Liz Garbus)。
指数:93.6

Graphical abstract: Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir
Open Access Edge Article

Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes

3.2 深化重要领域和关键环节改革
5. How to play poker
Actor in a Comedy Series: Jeffrey Tambor, “Transparent”

Graphical abstract: Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes
Accepted Manuscript - Paper

A Digital Protein Microarray for COVID-19 Cytokine Storm Monitoring

Open Access Paper

Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)

There was no indication of the identity of the kidnappers or their motive.

Graphical abstract: Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)
Paper

A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood

The current El , a naturally recurring phenomenon that warms the Pacific Ocean, was probably only responsible for about 10 per cent of 2015’s record-breaking temperatures, he added.

Graphical abstract: A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood
Open Access Paper

Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations

该书反映了部分群体越来越担忧自动化可能对就业——从制造业到专业服务领域的就业——产生的负面影响。该书英国版的副标题警告了“大规模失业的威胁”,美国版的副标题则预言了“一个失业的未来”。
In a humiliating 111-77 loss to the Golden State Warriors at Oracle Arena, Bryant shot 1-of-14 from the field, including 1-of-7 from 3-point range, and scored four points. He also shot 1-of-14 in a loss last season to the San Antonio Spurs.

Graphical abstract: Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations
Open Access Paper

The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives

It was also the "most liked" tweet of the year, with 4.59 million likes.
联系方式:Staci Donegan and Peter Westley, Celia Dunn Sotheby’s International Realty, (912) 247-2052 / (912) 660-5169; celiadunnsir.com
查斯特·班宁顿
Consumer prices rose 2.3 per cent year-on-year, more than expectations of 1.8 per cent. That is the biggest rise since July 2014. They had risen 1.8 per cent in January.

Graphical abstract: The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives
Open Access Paper

Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease

切实落实脱贫攻坚责任制,实施最严格的评估考核,严肃查处假脱贫、“被脱贫”、数字脱贫,确保脱贫得到群众认可、经得起历史检验。
adj. 有限的,被限制的

Graphical abstract: Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease
Open Access Paper

Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro

谎言4:太感谢了!我很喜欢!说谎原因:告诉别人他们送的礼物一团糟会让我看起来像是冷血的混蛋。
麦肯锡将于3月宣布当选者,预计此人将对麦肯锡的发展方向产生重大影响。一些内部人士倾向于那些在快速增长领域(比如数据分析)具备专长的候选人,而其他人想要一位可以维护公司品牌的传统主义者。

Graphical abstract: Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro
Open Access Paper

Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein

《固定电话》

Graphical abstract: Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein
Paper

Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide

1.和平年代
中国的军队会获得更多的投入,从而增加更为先进的飞机和战舰。
Whatever happened to ‘Never complain; never explain' – the unofficial motto of the House of Windsor?
单词elite 联想记忆:

Graphical abstract: Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide
Open Access Paper

Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses

However, the economists polled expect slightly higher growth rates and substantially higher inflation over 2016.
Huawei, the Chinese technology group, has taken market share from both Apple and Samsung, according to BrandZ.

Graphical abstract: Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses
Open Access Paper

The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor

不存在什么人民,这是想象出来的实体。
The reason why Blake looks the same today as he did in high school is because he's only four years removed from his high school years. Just imagine how monstrous Blake will look with another year or two of NBA training under his belt.
Bernard Baumohl, chief global economist of the Economic Outlook Group, said he is even more optimistic. "The next two years could be the best two we have seen in at least a decade," he said. "There is clearly a lot of evidence the economy is gaining a lot of momentum."

Graphical abstract: The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor
Open Access Paper

Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study

毋庸置疑,改造比创造容易。任何曾经对着白纸一筹莫展的人都知道这一点。但是,在过去七年里,时尚界对60年代的普遍模仿至少暴露出,这个行业缺乏想象力——不只是对于服装和消费者缺乏想象力,而且对于文化与服装的关系也缺乏想象力。
5. Broadcaster
It was Somerset Maugham who said the French Riviera is “a sunny place for shady people” – and looking around at all the 'models' in the hotel lobbies and the men in dark sunglasses who seemed to know them, I knew what he meant. Behind the festival's shiny facade, there is an unseemly side – and beneath the azure waters, a polluted mess. The French diver and environmentalist Laurent Lombard's video of the Cannes seabed strewn with waste and debris went viral before the festival began. We were assured there was no danger to swimmers, and the mayor had it cleaned up according to the Daily Mail – but the Med had certainly lost some of its sparkle.

Graphical abstract: Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study
Open Access Paper

Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework

该王储称,当局可通过和解收回多达1000亿美元。
n. 紧张,压力

Graphical abstract: Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework
Open Access Paper

Several coumarin derivatives and their Pd(II) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach

Coumarin derivatives and their Pd(II)-complexes have shown a higher binding potential towards SARS-CoV-2 Mpro than chloroquine/cinanserin along with lower toxicity.

Graphical abstract: Several coumarin derivatives and their Pd(ii) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach
Open Access Paper

Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors

Sesquiterpenes, 8α-anisate-dauc-4-ene-3,9-dione (webiol anisate) (1) and 10α-acetoxy-6α-benzoate-jaeschkeanadiol (2) as well as several analogues (3–12) were root extracted from Ferula vesceritensis.

Graphical abstract: Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors
Open Access Paper

Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins

Design of 2-phenylquinazolin-4(3H)one-trihydroxyphenyl Schiff base conjugates as COVID-19 therapy.

Graphical abstract: Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins
Open Access Paper

Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform

The unprecedented declines have raised worries that the reserves could quickly evaporate if capital outflows continue and the central bank continues to defend the exchange rate. Most analysts believe the central bank will be forced to curtail its intervention in order to prevent further depletion of its reserves.
But a quick look at the changing skyline betrays a frustrating reality: Those shiny new towers have failed to deliver the type of housing most New Yorkers can afford. “There is a disconnect between what we’re building and what we need to build,” said Jonathan J. Miller, the president of the appraisal firm Miller Samuel. “2015 is going to be more of that.”
adj. 能生产的,有生产价值的,多产的

Graphical abstract: Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform
Open Access Paper

A modular microarray imaging system for highly specific COVID-19 antibody testing

较为大胆的律师将开始采用更为“科幻”的程序,这些程序宣称在上法庭前就能预测法律纠纷的结果——通过分析类似案件和过往裁决、反对方策略和胜诉/败诉统计数据、某些律师在某些法官面前的成功率等等。
尽管很多人总把保时捷与纯性能车联系在一起,但近年来保时捷扩大了他们的阵容,包括帕纳梅拉,即为上图的豪华车型,除此外还有卡宴和小卡宴SUV。根据多数评论家,帕纳梅拉不仅继承了保时捷强大的性能,还满足了使用者对高端内置和联网特性的需求。

Graphical abstract: A modular microarray imaging system for highly specific COVID-19 antibody testing
Open Access Paper

Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms

50个最优秀的“无工作经验要求”项目的所有毕业生中,三分之一以上毕业于英国的商学院。英国的商学院还吸引了近一半的女学生以及近一半的国际学生。实际上,2014年一个英国“无工作经验要求”金融硕士项目招收的学生中,有94%来自海外。这些学生当中约有85%来自欧洲经济区(European Economic Area)以外,55%来自中国内地。
The Lost Tomb
自2003年以来,上海软科教育信息咨询有限公司就根据第三方的数据,开始发布全球500强高校榜单。

Graphical abstract: Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms
Open Access Paper

Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening

而在非手术整形中,注射肉毒杆菌和激光脱毛依然是最受欢迎的。

Graphical abstract: Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening
From the themed collection: 房企能打的擦边球,全被杜绝
Open Access Paper

Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations

A combination of Autodock Vina and FPL calculations suggested that periandrin V, penimocycline, cis-p-Coumaroylcorosolic acid, glycyrrhizin, and uralsaponin B are able to bind well to SARS-CoV-2 Mpro.

Graphical abstract: Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations
Open Access Paper

Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets

Belgium, for example, has less than a tenth of the population of Russia, its rival in the group stage, but is regarded as a far greater threat. And then there is Uruguay, which despite fewer than 4 million citizens -- barely a sixth of the population of greater S?o Paulo -- is one of the teams Brazil would least like to meet on its way to the final. How is this so?
Writing for a Variety Special: Patton Oswalt, “Patton Oswalt: Talking for Clapping”

Graphical abstract: Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets
Open Access Paper

A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation

productive
['elig?nt]

Graphical abstract: A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation
Open Access Paper

An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19

3′-Hydroxy-4′-methoxy-chroman-7-O-β-D-glucopyranoside 4, together with three known compounds, ferulic acid heptyl ester 1, naringenin 2, and 4,2′,4′-trihydroxy-6′-methoxychalcone-4′-O-β-D-glucopyranoside 3, was isolated from peach fruits.

Graphical abstract: An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19
Open Access Paper

Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies

安妮-西尔万沙萨尼(Anne-Sylvaine Chassany)
This habit can seriously hurt you in a work setting. If you’re one of those folks who believes that you do your best work at the last minute and put off projects or assignments until the day (or hour) before they’re due, you may not be aware of the impact your habit is having on your co-workers.If your last-minute rush requires others to work quickly, you will likely anger them, and you’ll be the first one blamed when a project fails or isn’t completed on time.

Graphical abstract: Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies
Paper

Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material

6.Put people first
2015年最需要迎头赶上的品牌:由于产品线陈旧,大众今年的销量下降了11%,影响了费迪南德o皮切的“称霸全球”计划。沃尔沃的销量则下跌了17%,自从被中国车企收购后,该公司至今还没有任何进步。

Graphical abstract: Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material
Open Access Paper

A facile assay for rapid detection of COVID-19 antibodies

收入最高的十位模特中有九位都在内衣品牌维多利亚的秘密有相应的工作,大码模特阿什莉是唯一的例外。

Graphical abstract: A facile assay for rapid detection of COVID-19 antibodies
From the themed collection: 广东保障城市停车场建设用地
Open Access Paper

Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses

Gitanjali won a $25,000 prize for scooping the top award.
Traditionalists include George Clooney, whose awards – best picture for Argo and best supporting Actor for Syriana – are in his library at home, and Dustin Hoffman, whose two best actor awards – the first for Kramer vs. Kramer in 1980 and the second for Rain Man nine years later, are kept in his study.
将这些类似的信号通过编程的方式写入造假肢,会给截肢者带来和以前研发出来的产品完全不同的假肢。
3.人工胰腺

Graphical abstract: Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses
Open Access Paper

Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2

['d?u:?lri]

Graphical abstract: Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2
Open Access Paper

Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease

经济运行缓中趋稳、稳中向好;
他们两个自称拥有着世界上最大的两个粉丝基础。但是周日晚上,在伦敦温布利SSE竞技场上举行的2017年欧洲音乐大奖中,Shawn Mendes夺得桂冠, Taylor Swift在她参选的五个奖项中纷纷落选。
Stock pickers encountered difficulty this year in part because of concentration at the top of the market. Just five stocks—Apple, Berkshire Hathaway, Johnson & Johnson, Microsoft, and Intel— accounted for 20% of the market’s gains. If you weren’t at least equally weighted toward them, you had virtually no shot at making up for missing their enormous, index-driving gains. A majority of the market’s stocks did not perform nearly as well. According to the Leuthold Group, only 30% of S&P 1500 stocks posted gains exceeding the index itself. You’d have to go back to 1999 to see anything like this.

Graphical abstract: Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease
Open Access Paper

Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19

汉达·阿亚里(Henda Ayari)
所有这些合数值都比去年同期高,其中市场价值增幅最大(比去年同期增长13%)。这些公司在全球总共雇用了9000万人。

Graphical abstract: Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19
Paper

Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties

“My manifesto with Summly was to get our technology into as many users’ hands as possible,” Mr D’Aloisio said, pointing to Yahoo’s hundreds of millions of users. “With Yahoo’s reputation as a content portal, we have an opportunity to fundamentally change the way content is consumed.”
After a run with One Direction, Harry Styles could have gone anywhere he wanted.

Graphical abstract: Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties
Open Access Paper

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease.

Graphical abstract: Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease
Paper

Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract

桑迪已经造成大规模损害,很可能带来更多灾害。

Graphical abstract: Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract
Open Access Paper

Anti-HIV drug repurposing against SARS-CoV-2

fatigue
7. 克里斯汀?斯图尔特
Roula Khalaf

Graphical abstract: Anti-HIV drug repurposing against SARS-CoV-2
Paper

Length-scale dependence of protein hydration-shell density

accomplished
在这两个新指标方面,英国商学院的表现都优于法国商学院。在职业发展方面表现最好的英国商学院——华威商学院(Warwick Business School)在这一指标的总体排名中位居第二,高于法国在这方面表现最好的巴黎高等商学院(HEC Paris) 30个名次。在毕业后首份工作薪资与当下薪资比较方面,英国商学院校友的薪资增幅更大,为62%,法国商学院校友的薪资增幅为45%。然而,英国商学院校友的平均薪资仍低于与法国商学院校友,分别为5.5万美元和6.4万美元。
被调查的34个城市间的差距就更大了。北京市平均年终奖超过1.58万元人民币,超过了年终奖最低的沈阳市的三倍。沈阳市是中国东北铁锈地带辽宁省的省会。
intimidating

Graphical abstract: Length-scale dependence of protein hydration-shell density
Open Access Paper

High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus

考虑到猛龙现有的轮转人员,伊巴卡和塔克的到来使猛龙的防守大幅度提升了。鉴于洛瑞和德马尔-德罗赞一到季后赛得分效率就下降的黑历史,这两笔交易也给了主教练德韦恩-凯西足够的武器用来拿下那些季后赛胜利。
圣加伦大学校友在毕业3年后的平均年薪增至10.2万美元,去年这个数字为9万美元。

Graphical abstract: High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus
From the themed collection: 地暖致癌 地板是助推者
Paper

A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor

该项目的另一个好处在于,它鼓励了职业灵活性,让年轻人对曲折的职业道路有所准备,而后者可能在现代职场中是必不可少的。
过去十年中,只有3颗10克拉级且硬度相当的鲜彩蓝钻被拍卖,3颗都未达到12克拉,而且有瑕疵。
Traditionally Chinese universities scored less well in international ranking tables compared to US and European incumbents in levels of teaching and research.

Graphical abstract: A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor
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China's box office sales hit a record high in 2015, by pulling in 44 billion yuan, or some 6.8 billion US dollars, with domestic films accounting for a large chunk of that growth.
在20世纪90年代,罗斯把它应用到如何把美国医学生分配到医院。他开发了一种新的算法被全国驻地医师匹配程序所采用,这有助于把驻院医师分配到合适的医院。

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